Antioch on the Orontes (Greek: Αντιόχεια η επί Ορόντου; Latin: Antiochia ad Orontem) was one of the most important cities of the Graeco-roman period. The ancient city stood on the eastern side of the Orontes River. It is currently partly covered by the modern city of Antakya.
It was founded in the 4th century BC by Seleucus I Nicator. Antioch eventually rivaled Alexandria as the chief city of the Near East and played a particularly strong role in the late Empire.